Prevalence & Sequelae Oral & Systemic Disease bullet Chapter Objectives bullet Nutrition bullet Substance Use and Abuse bullet Iatrogenic bullet Caregiver/Patient Limitations bullet Healthcare provider challenges bullet Bacterial Spread bullet The Role of Inflammation bullet Inflammation & Systemic Disease bullet Obesity & Diabetes bullet Heart Disease bullet Cost Containment bullet Adverse Pregnancy Outcomes bullet Menopause bullet Rheumatoid Arthritis bullet Infectious Disease bullet Tooth Loss and All-Cause Mortality Role of the Primary Care Clinician Summary & Assessment Adverse Pregnancy Outcomes