The use of fluoride, both through dietary and topical applications, has led to dramatic drops in caries rates.
Through topical mechanisms, the main effect, fluoride works by:
Through systemic mechanisms, the lesser effect, fluoride works by:
Topical Fluoride is the most beneficial and is obtained through:
Systemic Fluoride is obtained through:
Centers for Disease Control and Prevention (1999) Achievements in public health, 1990–1999: fluoridation
of drinking water to prevent dental caries. MMWR Morb Mortal Wkly Rep 48:933–940.
Weyant RJ, Tracy SL, Anselmo TT et al. Topical fluoride for caries prevention: executive summary of the updated clinical recommendations and supporting systematic review. American Dental Association Council on Scientific Affairs Expert Panel on Topical Fluoride Caries Preventive Agents. J Am Dent Assoc. 2013. 144(11):1279-91.