An example of severe oral consequences resulting from substance use and abuse is "Meth Mouth". Meth mouth is seen in methamphetamine (aka meth, speed, ice, crystal, crank) users when the drug is smoked, snorted, injected, or taken orally.
Rapid onset oral devastation is mainly a problem of teens and young adults. Up to 5% of the 12-to-40-year old population report having used methamphetamines.
Research has shown that behavioral factors, such as smoking, consuming sugary beverages, and poor oral hygiene, are more important than a direct drug effect of methamphetamines.
Curtis EK. Meth mouth: a review of methamphetamine abuse and its oral manifestations. Gen Dent. 2006; 54(2): 125-9.
Clague J, Belin TR, Shetty V. Mechanisms underlying methamphetamine-related dental disease.. J Am Dent Assoc. 2017. 148(6): 377-386.
Spolsky VW, Clague J, Murphy DA, Vitero S, Dye BA, Belin TR, Shetty V. Periodontal status of current methamphetamine users. J Am Dent Assoc. 2018; 149(3): 174-183.