Recent studies show that 7 out of 10 elderly take at least one prescription medication, and up to 20% take five or more prescription drugs. The most common medications taken by those over age 65 include lipid lowering drugs, medications for diabetes, and beta-blockers.
|Phenytoin, methotrexate, calcium channel blockers||Gingival Overgrowth|
|Chemotherapy and radiation therapy||Stomatitis and mucositis|
|Nifedipine in type II diabetics||Periodontal disease|
|Sugar containing medication preparations, e.g., syrups||Dental Caries|
|Progesterone, nitrates, beta and calcium channel blockers||Dental erosions due to gastric reflux|
|Antihypertensives, antidepressants, antihistamines, diuretics||Xerostomia|
Zhang X, Hamadeh IS, Song S, et al. Osteonecrosis of the Jaw in the United States Food and Drug Administration's Adverse Event Reporting System (FAERS). J Bone Miner Res. 2016;31(2):336-340. doi:10.1002/jbmr.2693
Aghaloo TL, Tetradis S. Osteonecrosis of the Jaw in the Absence of Antiresorptive or Antiangiogenic Exposure: A Series of 6 Cases. J Oral Maxillofac Surg. 2017;75(1):129-142.
Hales CM, Servais J, Martin CB, Kohen D. Prescription drug use among adults aged 40–79 in the United States and Canada. NCHS Data
Brief, no 347. Hyattsville, MD: National Center for Health Statistics. 2019.
Steinman MA, Hanlon JT. Managing medications in clinically complex elders: there's got to be a happy medium. JAMA 2010; 304(14): 1592-1601.
Mabi L, Papas A. Oral Implications of Polypharmacy in the Elderly. Dental Clinics of North America. 2014; 58(4): 783-796.