Vascular Disease

Periodontal disease is associated with coronary artery disease and cerebrovascular disease.

  • Studies support an association between PD and ASVD, but not a causative relationship.
  • Inflammatory cytokines implicated in atherogenesis are produced in patients with periodontal disease.
  • Treatment of periodontal disease has not been shown to date to reduce cardiovascular risk.


Strokes can result in multiple oral problems, such as:

  • Oral sensory and motor deficits
  • Poor tongue function and lip seal
  • Dysphagia
  • Reduced oral clearance of foods and increased food packing
  • Reduced dexterity negatively affecting ability to perform oral hygiene
  • Increased caries and periodontal disease risk

Food Packing

B.J. Brown, RDH, MS
B.J. Brown, RDH, MS


Lockhart PB, et al. Periodontal Disease and Atherosclerotic Disease: Does the Evidence Support an Independent Association? Circulation. 2012. Accessed on 9/20/2021.

Kebschull M, Demmer RT, Papapanou PN, "Gum Bug, Leave my Heart Alone!" Epidemiologic and Mechanistic Evidence Linking Periodontal Infections and Atherosclerosis. J of Dental Research. 2010;89:879-902.  

Liljestrand JM, Paju S, Pietiäinen M, et al. Immunologic burden links periodontitis to acute coronary syndrome. Atherosclerosis.2018; 268: 177-184.

Meurman JH. A role for oral health personnel in stroke prevention. Compend Contin Educ Dent. 2017; 38(8 Suppl): 26-28. 

Li C, Lv Z, Shi Z, Zhu Y, Wu Y, Li L, Iheozor-Ejiofor Z. Periodontal therapy for the management of cardiovascular disease in patients with
chronic periodontitis. Cochrane Database of Systematic Reviews 2014, Issue 8. Art. No.: CD009197. DOI: