Pregnancy Granuloma

Pregnancy granuloma occurs in 5% of pregnant women. It is indistinguishable from pyogenic granuloma, and is a rapidly growing, tumor-like lesion that develops as a response to local irritation such as poor hygiene, overhanging restorations, or trauma. Increasing estrogen and progesterone levels during pregnancy exacerbate the condition.

Symptoms

  • Erythematous, nonpainful, smooth, or lobulated mass
  • Bleeds easily when touched
  • Most frequently develops on the gingiva, but less common locations include the lip, tongue, or buccal mucosa
  • May vary in size from a few millimeters to several centimeters in diameter
  • Usually appears between second and eighth month of pregnancy

Treatment

  • Offer reassurance
  • Observe unless lesions are bleeding excessively, interfere with eating, or do not resolve spontaneously after delivery
  • Lesions can be treated by conservative surgical excision
  • Recurrence is uncommon unless the lesion is incompletely removed or the source of irritation remains
  • Lesions excised during pregnancy recur more frequently

Large Granuloma

Brad Neville, DDS
Brad Neville, DDS

References

Jafarzadeh H, Sanatkhani M, Mohtasham N, et al. Oral Pyogenic Granuloma: A Review.  J Oral Sci. 2006; 48:167-175.

Gonsalves, W.C., Chi, A.C., Neville, B.W. Common Oral Lesions: Part II. Masses and Neoplasia. Am Fam Physician. 2007;75(4):509-512.